Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes.

Developmental biology - 1 Jan 2011

Zhao Qingshi, Beck Amanda J, Vitale Joseph M, Schneider Joel S, Gao Shumin, Chang Corey, Elson Genie, Leibovich Samuel J, Park Ji Yeon, Tian Bin, Nam Hyung-song, Fraidenraich Diego

Abstract excerpt

The Id1 and Id3 genes play major roles during cardiac development, despite their expression being confined to non-myocardial layers (endocardium-endothelium-epicardium). We previously described that Id1Id3 double knockout (dKO) mouse embryos die at mid-gestation from multiple cardiac defects, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cell Lineage
Share to Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Heart Diseases

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Myocardium

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 20937270
DOI: 10.1016/j.ydbio.2010.10.004
PMCID: PMC2993814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20937270-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes.PMID 20937270Read ↗

Hematopoietic Id Deletion Triggers Endomyocardial Fibrotic and Vascular Defects in the Adult Heart.Semantic proximity Read ↗

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.Semantic proximity Read ↗

Inhibitor of DNA binding in heart development and cardiovascular diseasesSemantic proximity Read ↗

Mekk3 is essential for early embryonic cardiovascular development.Semantic proximity Read ↗

Irx3 is required for postnatal maturation of the mouse ventricular conduction systemSemantic proximity Read ↗

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3Semantic proximity Read ↗

Id genes are essential for early heart formation.Semantic proximity Read ↗

Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3Semantic proximity Read ↗

Role of Id proteins in embryonic and tumor angiogenesis.Semantic proximity Read ↗

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.Semantic proximity Read ↗

Endothelial lipid phosphate phosphatase-3 deficiency that disrupts the endothelial barrier function is a modifier of cardiovascular development.Semantic proximity Read ↗

Roles of fibronectin isoforms in neonatal vascular development and matrix integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.