Article
Use of monozygotic twins in search for breast cancer susceptibility loci.
Twin research : the official journal of the International Society for Twin Studies - 1 Aug 2001
Försti A, Jin Q, Sundqvist L, Söderberg M, Hemminki K
Abstract excerpt
We have used Swedish monozygotic twins concordant for breast cancer to study genetic changes associated with the development of breast cancer. Because loss of heterozygosity (LOH) at a specific genomic region may reflect the presence of a tumour suppressor gene, loss of the same allele in both of the twins concordant for breast cancer may pinpoint a tumour suppressor gene that confers a strong predisposition to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
