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Article

Heritable breast cancer in twins.

British journal of cancer - 29 Jul 2002

Mack T M, Hamilton A S, Press M F, Diep A, Rappaport E B

Abstract excerpt

Known major mutations such as BRCA1/2 and TP53 only cause a small proportion of heritable breast cancers. Co-dominant genes of lower penetrance that regulate hormones have been thought responsible for most others. Incident breast cancer cases in the identical (monozygotic) twins of representative cases reflect the entire range of pertinent alleles, whether acting singly or in combination. Having reported the rate...

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Identifiers

PMID: 12177798
DOI: 10.1038/sj.bjc.6600429
PMCID: PMC2364223

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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