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Article

Degeneration of a homing endonuclease and its target sequence in a wild yeast strain.

Nucleic acids research - 15 Oct 2001

Gimble F S

Abstract excerpt

Mobile introns and inteins self-propagate by 'homing', a gene conversion process initiated by site-specific homing endonucleases. The VMA intein, which encodes the PI-SceI endonuclease in Saccharomyces cerevisiae, is present in several different yeast strains. Surprisingly, a wild wine yeast (DH1-1A) contains not only the intein(+) allele, but also an inteinless allele that has not undergone gene conversion. To...

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Identifiers

PMID: 11600710
DOI: 10.1093/nar/29.20.4215
PMCID: PMC60219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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