Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae.

doi:10.1038/357301a0

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Article

Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae.

Nature - 28 May 1992

Gimble F S, Thorner J

Abstract excerpt

An unusual protein splicing reaction joins the N-terminal segment (A) and the C-terminal segment (C) of the 119K primary translation product (ABC) of the yeast VMA1 gene to yield a 69K vacuolar H(+)-ATPase subunit (AC) and an internal 50K polypeptide (B). This 50K protein is a site-specific DNA e...

Topics

Alleles
Base Sequence
Chromosome Deletion
DNA, Fungal
Deoxyribonuclease I
Escherichia coli
Gene Conversion
Genes, Fungal
Intracellular Membranes
Introns
Meiosis
Molecular Sequence Data
Plasmids
Proton-Translocating ATPases
Recombinant Proteins
Saccharomyces cerevisiae
Spores, Fungal
Transformation, Bacterial

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Open in PubMed

Identifiers

PMID: 1534148
DOI: 10.1038/357301a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1534148-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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