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Article

Homing endonucleases residing within inteins: evolutionary puzzles awaiting genetic solutions.

Biochemical Society transactions - 1 Jan 2011

Barzel Adi, Naor Adit, Privman Eyal, Kupiec Martin, Gophna Uri

Abstract excerpt

Inteins are selfish genetic elements that disrupt the sequence of protein-coding genes and are excised post-translationally. Most inteins also contain a HEN (homing endonuclease) domain, which is important for their horizontal transmission. The present review focuses on the evolution of inteins and their nested HENs, and highlights several unsolved questions that could benefit from molecular genetic approaches....

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PMID: 21265767
DOI: 10.1042/BST0390169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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