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Article

ASK1 resistant neuroblastoma is deficient in activation of p38 kinase.

Cell death and differentiation - 1 Oct 2001

Arvidsson Y, Hamazaki T S, Ichijo H, Funa K

Abstract excerpt

Apoptosis Signal-regulating Kinase 1 (ASK1) is known to either induce apoptosis or differentiation in various cell lines of neuronal origin. We analyzed the effect of the constitutively active mutant of ASK1 (ASK1-Delta N) in an adenoviral vector in four neuroblastoma cell lines, two murine, C1300 and NXS2, and two human, SH-SY5Y and IMR-32. Already after 24 h upon infection, C1300 and SH-SY5Y cells arrested in...

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PMID: 11598801
DOI: 10.1038/sj.cdd.4400922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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