Article
Mechanism of MASH1 induction by ASK1 and ATRA in adult neural progenitors.
Molecular and cellular neurosciences - 1 Oct 2007
Elmi Muna, Faigle Roland, Yang Weiwen, Matsumoto Yoshiki, Rosenqvist Erica, Funa Keiko
Abstract excerpt
The molecular mechanisms underlying differentiation and lineage commitment in neural stem cells are just beginning to be understood, however the molecules involved in this process and their functions remain largely unknown. Here we studied the effects and downstream signals of apoptosis signal-regulating kinase 1 (ASK1) together with all-trans retinoic acid (ATRA) on neuronal differentiation in adult...
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