Article
Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals.
Molecular biology of the cell - 1 Oct 2001
Leenders A G, Lopes da Silva F H, Ghijsen W E, Verhage M
Abstract excerpt
The rab family of GTP-binding proteins regulates membrane transport between intracellular compartments. The major rab protein in brain, rab3A, associates with synaptic vesicles. However, rab3A was shown to regulate the fusion probability of synaptic vesicles, rather than their transport and docking. We tested whether rab3A has a transport function by analyzing synaptic vesicle distribution and exocytosis in rab3A...
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