The role of Rab3A in neurotransmitter release.

doi:10.1038/369493a0

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Article

The role of Rab3A in neurotransmitter release.

Nature - 9 Jun 1994

Geppert M, Bolshakov V Y, Siegelbaum S A, Takei K, De Camilli P, Hammer R E, Südhof T C

Abstract excerpt

The small GTP-binding protein Rab3A is a Rab family member that is abundant in brain synaptic vesicles. Here we show that mice in which the rab3A gene has been mutated by homologous recombination do not express Rab3A but are viable and fertile. Electrophysiological recordings in hippocampal CA1 p...

Topics

Adaptor Proteins, Signal Transducing
Animals
Electrophysiology
Exocytosis
GTP-Binding Proteins
In Vitro Techniques
Mice
Mutation
Nerve Tissue Proteins
Neurotransmitter Agents
Pyramidal Cells
Synaptic Transmission
Vesicular Transport Proteins
rab GTP-Binding Proteins
rab3 GTP-Binding Proteins
Rabphilin-3A

Source

Open in PubMed

Identifiers

PMID: 7911226
DOI: 10.1038/369493a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7911226-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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