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Article

Presynaptic Kv3 channels are required for fast and slow endocytosis of synaptic vesicles.

Neuron - 17 Mar 2021

Wu Xin-Sheng, Subramanian Shobana, Zhang Yalan, Shi Bo, Xia Jessica, Li Tiansheng, Guo Xiaoli, El-Hassar Lynda, Szigeti-Buck Klara, Henao-Mejia Jorge, Flavell Richard A, Horvath Tamas L, Jonas Elizabeth A, Kaczmarek Leonard K, Wu Ling-Gang

Abstract excerpt

Since their discovery decades ago, the primary physiological and pathological effects of potassium channels have been attributed to their ion conductance, which sets membrane potential and repolarizes action potentials. For example, Kv3 family channels regulate neurotransmitter release by repolarizing action potentials. Here we report a surprising but crucial function independent of potassium conductance: by...

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Identifiers

PMID: 33508244
DOI: 10.1016/j.neuron.2021.01.006
PMCID: PMC7979485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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