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Article

Early detection of mixed mutations selected by antiretroviral agents in HIV-infected primary human lymphocytes.

Antiviral chemistry & chemotherapy - 1 Jan 2001

Schinazi R F, Schlueter-Wirtz S, Stuyver L

Abstract excerpt

A growing concern in the pursuit of new therapies for HIV-1 infection is the potential for the virus to develop drug resistance. With the advent of modern antiretroviral therapy and the common use of combined modalities, it is difficult to identify in the clinic the mutations associated with a specific drug. In general, drug selection of mutants using a relevant cell system, such as primary human lymphocytes, is...

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PMID: 11594690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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