Article
Genotypic resistance of archived and circulating viral strains in the blood of treated HIV-infected individuals.
Journal of acquired immune deficiency syndromes (1999) - 15 Apr 2007
Turriziani Ombretta, Bucci Mauro, Stano Armando, Scagnolari Carolina, Bellomi Francesca, Fimiani Caterina, Mezzaroma Ivano, D'Ettorre Gabriella, Brogi Andrea, Vullo Vincenzo, Antonelli Guido
Abstract excerpt
The aim of this study was to evaluate patterns of antiretroviral resistance of HIV-1 in peripheral blood mononuclear cells (PBMCs) and in the plasma of patients whose therapeutic regimen is failing. Plasma and PBMC samples were collected from 95 HIV-infected patients undergoing long-term treatment. Genotyping of the reverse transcriptase (RT) and protease genes of HIV-1 was undertaken using the fluorescent...
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