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Article

Human immunodeficiency virus type 1: resistance to nucleoside analogues and replicative capacity in primary human macrophages.

Journal of virology - 1 May 2007

Perez-Bercoff Danielle, Wurtzer Sébastien, Compain Séverine, Benech Henri, Clavel François

Abstract excerpt

Antiretroviral treatment failure is associated with the emergence of resistant human immunodeficiency virus type 1 (HIV-1) populations which often express altered replicative capacity (RC). The resistance and RC of clinical HIV-1 strains, however, are generally assayed using activated peripheral blood mononuclear cells (PBMC) or tumor cell lines. Because of their high proliferation rate and concurrent high...

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Identifiers

PMID: 17287264
DOI: 10.1128/JVI.01620-06
PMCID: PMC1900139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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