Article
Loss of heterozygosity analysis defines a 3-cM region of 15q commonly deleted in human malignant mesothelioma.
Oncogene - 27 Sept 2001
De Rienzo A, Balsara B R, Apostolou S, Jhanwar S C, Testa J R
Abstract excerpt
Previous comparative genomic hybridization and allelic loss analyses demonstrated frequent deletions from 15q11.1-15 in malignant mesothelioma. Recurrent losses of 15q11-22 have also been reported in several other tumor types such as breast and colorectal cancers. To more precisely map the commonly deleted region, we have performed a high density loss of heterozygosity analysis of 46 malignant mesotheliomas,...
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