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Article

Loss of heterozygosity analysis of 13q and 14q in human malignant mesothelioma.

Genes, chromosomes & cancer - 1 Jul 2000

De Rienzo A, Jhanwar S C, Testa J R

Abstract excerpt

Cytogenetic investigations of malignant mesothelioma (MM) have revealed frequent losses in chromosomes 13 and 14, suggesting that inactivation of tumor suppressor genes (TSGs) residing in these chromosomes may contribute to mesothelial cell tumorigenesis. To define the shortest region of overlap (SRO) of deletions from these chromosomes, we performed loss of heterozygosity (LOH) analyses on 30 MMs using 25...

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Identifiers

PMID: 10862040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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