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Article

Association of the APOE epsilon4 allele with disease activity in multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 1999

Evangelou N, Jackson M, Beeson D, Palace J

Abstract excerpt

OBJECTIVES: Allelic variants of the APOE gene are known to influence the course of many neurological diseases and there is increasing evidence that apolipoprotein E (APOE) is a pivotal component in reinnervation and dendritic remodelling after neuronal injury. Previous studies did not show significant differences in the APOE allele frequencies in multiple sclerosis compared with controls but did not examine for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10406990
DOI: 10.1136/jnnp.67.2.203
PMCID: PMC1736483

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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