Article
BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines.
Cancer - 1 Sept 2001
Bold R J, Virudachalam S, McConkey D J
Abstract excerpt
BACKGROUND: Programmed cell death (termed apoptosis) regulates normal tissue homeostasis. Loss of local paracrine signals and intercellular adhesion molecules are potent inducers of apoptosis and thereby eliminate normal cells that may have escaped beyond the confines of the local organ environment. Dysregulation in the expression of the BCL2 gene family, the prototypic regulators of apoptosis, is a common...
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