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Article

bcl-2 expression is reciprocal to p53 and c-myc expression in metastatic human colorectal cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jul 1998

Popescu R A, Lohri A, de Kant E, Thiede C, Reuter J, Herrmann R, Rochlitz C F

Abstract excerpt

Apoptosis (programmed cell death) inhibition may be an important mechanism by which gastrointestinal mucosal cells containing damaged DNA evade normal clearance mechanisms and grow to become invasive tumours. Since bcl-2 is an apoptosis inhibitor, bcl-2 mRNA expression was measured in 21 metastases of colorectal cancer using reverse transcription-polymerase chain reaction analysis. The mean bcl-2 mRNA expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 9849490
DOI: 10.1016/s0959-8049(98)00057-4

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DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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