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Article

Expression of phosphorylated Ser70 of Bcl-2 correlates with malignancy in human colorectal neoplasms.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2005

Kondo Eisaku, Miyake Takayoshi, Shibata Masao, Kimura Toshikazu, Iwagaki Hiromi, Nakamura Shin-Ichi, Tanaka Takehiro, Ohara Nobuya, Ichimura Koichi, Oka Takashi, Yanai Hiroyuki, Shibasaki Futoshi, Yoshino Tadashi

Abstract excerpt

PURPOSE: Bcl-2 is a model apoptosis suppressor postulated to promote tumorigenesis. Recently, it has been reported that Bcl-2 undergoes phosphoregulation of its Ser70 to substantially alter its molecular function. Previous studies further suggest that such phospho-Bcl-2 regulation may influence t...

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PMID: 16243795
DOI: 10.1158/1078-0432.CCR-05-0274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16243795-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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