Article
Bcl-2 expression is associated with lymph node metastasis in human ductal breast carcinoma.
International journal of cancer - 3 Jan 1995
Sierra A, Lloveras B, Castellsagué X, Moreno L, García-Ramirez M, Fabra A
Abstract excerpt
The Bcl-2 proto-oncogene product blocks apoptosis. We retrospectively studied Bcl-2 expression in 124 primary tumors from patients diagnosed with T1 (2 cm or less) breast carcinoma with (T1N1) or without (T1N0) lymph-node metastasis. Bcl-2 protein was detected by immunohistochemistry on paraffin-embedded tissue sections. Multivariate logistic regression modeling was used to estimate prevalence odds ratios for...
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