Article
Bcl-2 expression is associated with lymph node metastasis in human ductal breast carcinoma.
International journal of cancer - 3 Jan 1995
Sierra A, Lloveras B, Castellsagué X, Moreno L, García-Ramirez M, Fabra A
Abstract excerpt
The Bcl-2 proto-oncogene product blocks apoptosis. We retrospectively studied Bcl-2 expression in 124 primary tumors from patients diagnosed with T1 (2 cm or less) breast carcinoma with (T1N1) or without (T1N0) lymph-node metastasis. Bcl-2 protein was detected by immunohistochemistry on paraffin-...
Topics
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Cell Survival
- Female
- Gene Expression
- Humans
- Immunohistochemistry
- Lymph Nodes
- Lymphatic Metastasis
- Middle Aged
- Mutation
- Neoplasm Staging
- Neoplasms, Hormone-Dependent
- Proto-Oncogene Mas
- Proto-Oncogene Proteins