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Article

Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2.

The EMBO journal - 17 Sept 2001

Penela P, Elorza A, Sarnago S, Mayor F

Abstract excerpt

G-protein-coupled receptor kinase 2 (GRK2) plays a key role in the regulation of G-protein-coupled receptors (GPCRs). GRK2 expression is altered in several pathological conditions, but the molecular mechanisms that modulate GRK2 cellular levels are largely unknown. We recently have described that...

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Identifiers

PMID: 11566877
DOI: 10.1093/emboj/20.18.5129
PMCID: PMC125273

Genes

GRK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11566877-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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