Article
In vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column.
BMC genomics - 5 Dec 2014
Chatterjee Sumantra, Sivakamasundari V, Yap Sook Peng, Kraus Petra, Kumar Vibhor, Xing Xing, Lim Siew Lan, Sng Joel, Prabhakar Shyam, Lufkin Thomas
Abstract excerpt
BACKGROUND: Vertebrate organogenesis is a highly complex process involving sequential cascades of transcription factor activation or repression. Interestingly a single developmental control gene can occasionally be essential for the morphogenesis and differentiation of tissues and organs arising from vastly disparate embryological lineages. RESULTS: Here we elucidated the role of the mammalian homeobox gene Bapx1...
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