Cse1l is essential for early embryonic growth and development.

doi:10.1128/MCB.21.20.7020-7024.2001

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Article

Cse1l is essential for early embryonic growth and development.

Molecular and cellular biology - 1 Oct 2001

Bera T K, Bera J, Brinkmann U, Tessarollo L, Pastan I

Abstract excerpt

The CSE1L gene, the human homologue of the yeast chromosome segregation gene CSE1, is a nuclear transport factor that plays a role in proliferation as well as in apoptosis. CSE1 and CSE1L are essential genes in Saccharomyces cerevisiae and mammalian cells, as shown by conditional yeast mutants and mammalian cell culture experiments with antisense-mediated depletion of CSE1L. To analyze whether CSE1L is also...

Topics

Active Transport, Cell Nucleus
Alleles
Animals
Apoptosis
Blotting, Northern
Carrier Proteins
Cell Division
Cell Nucleus
Cellular Apoptosis Susceptibility Protein
Cloning, Molecular
Crosses, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Embryo, Mammalian

Genetic Vectors

Genotype

Heterozygote

Homozygote

Humans

Mice

Source

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Identifiers

PMID: 11564884
DOI: 10.1128/MCB.21.20.7020-7024.2001
PMCID: PMC99877

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