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Article

Na,K-ATPase is essential for embryonic heart development in the zebrafish.

Development (Cambridge, England) - 1 Dec 2003

Shu Xiaodong, Cheng Karen, Patel Neil, Chen Fuhua, Joseph Elaine, Tsai Huai-Jen, Chen Jau-Nian

Abstract excerpt

Na,K-ATPase is an essential gene maintaining electrochemical gradients across the plasma membrane. Although previous studies have intensively focused on the role of Na,K-ATPase in regulating cardiac function in the adults, little is known about the requirement for Na,K-ATPase during embryonic heart development. Here, we report the identification of a zebrafish mutant, heart and mind, which exhibits multiple...

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Share to Embryo, Nonmammalian
Share to Genes, Essential
Share to Heart

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

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Share to Sodium-Potassium-Exchanging ATPase

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Source

Identifiers

PMID: 14602677
DOI: 10.1242/dev.00844

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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