Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and Transcriptional Regulation of Megakaryocyte Differentiation

1 Sept 2001

Abstract excerpt

Megakaryocytes, among the rarest of hematopoietic cells, serve the essential function of producing numerous platelets. Genetic studies have recently provided rich insights into the molecular and transcriptional regulation of megakaryocyte differentiation and thrombopoiesis. Three transcription factors, GATA-1, FOG-1, and NF-E2, are essential regulators of distinct stages in megakaryocyte differentiation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Multiple Myeloma Research and Treatments
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment
Share to Platelet Disorders and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11553848
DOI: 10.1634/stemcells.19-5-397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and Transcriptional Regulation of Megakaryocyte DifferentiationPMID 11553848Read ↗

Megakaryopoiesis and Platelet Biology: Roles of Transcription Factors and Emerging Clinical Implications.Semantic proximity Read ↗

GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development.Semantic proximity Read ↗

Epigenetic regulation of megakaryopoiesis and platelet formationSemantic proximity Read ↗

Insights into Regulatory Factors in Megakaryocyte Development and Function: Basic Mechanisms and Potential TargetsSemantic proximity Read ↗

Maturation stage–specific regulation of megakaryopoiesis by pointed-domain Ets proteinsSemantic proximity Read ↗

Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2Semantic proximity Read ↗

Transcription factors in megakaryocytes and plateletsSemantic proximity Read ↗

NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytesSemantic proximity Read ↗

Hematopoietic transcription factor mutations: important players in inherited platelet defects.Semantic proximity Read ↗

Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturationSemantic proximity Read ↗

The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene ExpressionSemantic proximity Read ↗

Normal and malignant megakaryopoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.