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Article

Hematopoietic transcription factor mutations: important players in inherited platelet defects.

Blood - 25 May 2017

Songdej Natthapol, Rao A Koneti

Abstract excerpt

Transcription factors (TFs) are proteins that bind to specific DNA sequences and regulate expression of genes. The molecular and genetic mechanisms in most patients with inherited platelet defects are unknown. There is now increasing evidence that mutations in hematopoietic TFs are an important underlying cause for defects in platelet production, morphology, and function. The hematopoietic TFs implicated in...

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Identifiers

PMID: 28416505
DOI: 10.1182/blood-2016-11-709881
PMCID: PMC5445569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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