Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2

15 Aug 2000

Abstract excerpt

The cellular and molecular bases of platelet release by terminally differentiated megakaryocytes represent important questions in cell biology and hematopoiesis. Mice lacking the transcription factor NF-E2 show profound thrombocytopenia, and their megakaryocytes fail to produce proplatelets, the microtubule-based precursors of blood platelets. Using mRNA subtraction between normal and NF-E2-deficient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mast cells and histamine
Share to Platelet Disorders and Treatments
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10942379
DOI: 10.1182/blood.v96.4.1366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2PMID 10942379Read ↗

Molecular and Transcriptional Regulation of Megakaryocyte DifferentiationSemantic proximity Read ↗

Mice Lacking Transcription Factor NF-E2 Provide In Vivo Validation of the Proplatelet Model of Thrombocytopoiesis and Show a Platelet Production Defect That Is Intrinsic to MegakaryocytesSemantic proximity Read ↗

An essential role for α4A-tubulin in platelet biogenesisSemantic proximity Read ↗

A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease.Semantic proximity Read ↗

Post-translational polymodification of <i>β</i> 1 tubulin regulates motor protein localisation in platelet production and functionSemantic proximity Read ↗

A role for Rab27b in NF-E2-dependent pathways of platelet formation.Semantic proximity Read ↗

RNA translational regulation by CPEB4 orchestrates platelet function and pathophysiologySemantic proximity Read ↗

miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis.Semantic proximity Read ↗

Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes.Semantic proximity Read ↗

NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytesSemantic proximity Read ↗

Analysis of transcribed sequences from young and mature zebrafish thrombocytesSemantic proximity Read ↗

Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.