Article
GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development.
Advances in experimental medicine and biology - 1 Jan 2024
Takasaki Kaoru, Chou Stella T
Abstract excerpt
GATA1 is a highly conserved hematopoietic transcription factor (TF), essential for normal erythropoiesis and megakaryopoiesis, that encodes a full-length, predominant isoform and an amino (N) terminus-truncated isoform GATA1s. It is consistently expressed throughout megakaryocyte development and interacts with its target genes either independently or in association with binding partners such as FOG1 (friend of...
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