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Article

Stroke risk in siblings with sickle cell anemia.

Blood - 15 Mar 2003

Driscoll M Catherine, Hurlet Anne, Styles Lori, McKie Virgil, Files Beatrice, Olivieri Nancy, Pegelow Charles, Berman Brian, Drachtman Richard, Patel Kantilal, Brambilla Donald

Abstract excerpt

Cerebrovascular disease is a common cause of morbidity in sickle cell anemia (HbSS): approximately 10% of patients have a clinical stroke before 20 years of age, and another 22% have silent infarction on magnetic resonance imaging. The phenotypic variation among patients with HbSS suggests a role for modifier genes and/or environmental influences. To assess the familial component of clinical stroke in HbSS, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12609963
DOI: 10.1182/blood.V101.6.2401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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