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Article

Polymorphisms and expression of MMPs-TIMPs genes associated with cerebral ischemic stroke in young patients with sickle cell anemia

2022-11-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Sickle cell anemia (SCA) is a genetic disease with great clinical heterogeneity and few viable strategies for treatment; hydroxyurea (HU) is the only widely used drug. Thus, the study of single nucleotide polymorphisms (SNPs) and the gene expression of MMPs 1, 2, 9, 7 and TIMPs 1 and 2, which are involved in the regulation of extracellular matrix, inflammation, a...

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Literature Corpus work
9c3ed213-ab46-5720-a900-fe8ac7c7a6ad
DOI
10.21203/rs.3.rs-2285360/v1
Open publication

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Polymorphisms and expression of MMPs-TIMPs genes associated with cerebral ischemic stroke in young patients with sickle cell anemiaDOI 10.21203/rs.3.rs-2285360/v1
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