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Article

The I1307K APC polymorphism: prevalence in non-Ashkenazi Jews and evidence for a founder effect.

Genetic testing - 1 Jan 2001

Shtoyerman-Chen R, Friedman E, Figer A, Carmel M, Patael Y, Rath P, Fidder H H, Bar-Meir S, Theodor L

Abstract excerpt

A missense mutation within the APC gene, I1307K, was described in Ashkenazi individuals at risk for colorectal cancer (CRC) and in the general population. The anecdotal reporting of the occurrence of this mutation in some non-Ashkenazi individuals led us to hypothesize that within the Jewish peop...

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Identifiers

PMID: 11551102
DOI: 10.1089/109065701753145628

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11551102-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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