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Article

The influence of surface charges on quaternary ammonium block of shaker K+ channels.

The Journal of membrane biology - 1 Aug 2001

Quinn C C, Begenisich T

Abstract excerpt

Block of K+ channels can be influenced by the ability of charged residues on the protein surface to accumulate cationic blocking ions to concentrations greater than those in bulk solution. We examined the ionic strength dependence of extracellular block of Shaker K+ channels by tetraethylammonium ions (TEA+) and by a trivalent quaternary ammonium ion, gallamine3+. Wild-type and mutant channels were expressed in...

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Identifiers

PMID: 11547346
DOI: 10.1007/s00232-001-0047-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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