Article
Glycosylation increases potassium channel stability and surface expression in mammalian cells.
The Journal of biological chemistry - 7 Sept 2001
Khanna R, Myers M P, Lainé M, Papazian D M
Abstract excerpt
N-linked glycosylation is not required for the cell surface expression of functional Shaker potassium channels in Xenopus oocytes (Santacruz-Toloza, L., Huang, Y., John, S. A., and Papazian, D. M. (1994) Biochemistry 33, 5607-5613). We have now investigated whether glycosylation increases the stability, cell surface expression, and proper folding of Shaker protein expressed in mammalian cells. The turnover rates...
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