Article
Identification of chromosomal deficiencies that modify Drosophila mastermind mutant phenotypes.
Genesis (New York, N.Y. : 2000) - 1 Aug 2001
Yedvobnick B, Helms W, Barrett B
Abstract excerpt
Mastermind (Mam) is a component of Notch pathway signaling. In combination with the intracellular domain of Notch and Suppressor of Hairless, Mam forms a transcriptional activation complex. We have initiated a genetic approach to identify other loci involved in Mam function. The screen utilizes engineered mutations in Mam that derive from GAL4-UAS-directed expression of dominant negative constructs. When driven...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.