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Article

Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation.

Genetics - 1 Mar 2004

Yedvobnick Barry, Kumar Anumeha, Chaudhury Padmashree, Opraseuth Jonathan, Mortimer Nathan, Bhat Krishna Moorthi

Abstract excerpt

During neurogenesis in the ventral nerve cord of the Drosophila embryo, Notch signaling participates in the pathway that mediates asymmetric fate specification to daughters of secondary neuronal precursor cells. In the NB4-2 --> GMC-1 --> RP2/sib lineage, a well-studied neuronal lineage in the ventral nerve cord, Notch signaling specifies sib fate to one of the daughter cells of GMC-1. Notch mediates this process...

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Identifiers

PMID: 15082547
DOI: 10.1534/genetics.166.3.1281
PMCID: PMC1470772

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