Article
Mutation and expression analysis of the p73 gene in prostate cancer.
The Prostate - 1 May 1999
Yokomizo A, Mai M, Bostwick D G, Tindall D J, Qian J, Cheng L, Jenkins R B, Smith D I, Liu W
Abstract excerpt
BACKGROUND: p53 is the most highly mutated tumor suppressor gene in human cancers. Recently, p73, a first homologue of p53, was identified and considered to be an imprinted tumor suppressor gene. Thus, we analyzed the possible role of p73 in human prostate cancers. METHODS: We investigated the expression levels and expressed allelotypes and searched for mutations in the p73 gene in 27 primary prostate cancers...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.