Article
Analysis of HIV drug-resistant quasispecies in plasma, peripheral blood mononuclear cells and viral isolates from treatment-naive and HAART patients.
Journal of medical virology - 1 Oct 2001
Paolucci S, Baldanti F, Campanini G, Zavattoni M, Cattaneo E, Dossena L, Gerna G
Abstract excerpt
The pattern of HIV-1 reverse transcriptase and protease mutations conferring resistance to antiretroviral drugs was studied in five treatment-naive patients and five HIV-infected patients receiving HAART [two reverse transcriptase inhibitors + one protease inhibitor] for > or = 1 year. Direct seq...
Topics
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- DNA, Viral
- Drug Resistance, Microbial
- Female
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Leukocytes, Mononuclear
