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Article

Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report.

Retrovirology - 30 May 2008

Quan Yudong, Brenner Bluma G, Dascal André, Wainberg Mark A

Abstract excerpt

BACKGROUND: Although drug resistance is a major challenge in HIV therapy, the effect of drug resistance mutations on HIV evolution in vivo is not well understood. We have now investigated genetic heterogeneity in HIV-1 by performing drug resistance genotyping of the PR-RT regions of viruses derived from plasma and peripheral blood mononuclear cells (PBMCs) of a single patient who had failed multiple regimens of...

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Identifiers

PMID: 18513421
DOI: 10.1186/1742-4690-5-43
PMCID: PMC2426714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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