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Article

Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients.

Annals of internal medicine - 1 Jun 1998

Shafer R W, Winters M A, Palmer S, Merigan T C

Abstract excerpt

BACKGROUND: Drug resistance of HIV-1 is an obstacle to the long-term efficacy of antiretroviral therapy. OBJECTIVE: To characterize reverse transcriptase and protease genes of multidrug-resistant HIV-1 isolates. DESIGN: Descriptive case series. SETTING: Academic medical center. PATIENTS: Four consecutive patients with HIV-1 infection were selected because they had previously received many antiretroviral drugs and...

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9634429
DOI: 10.7326/0003-4819-128-11-199806010-00008

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Source receipt: pubmed, retrieved 7 Sept 2026.

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