Article
Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2005
Chew Choo Beng, Potter Simon J, Wang Bin, Wang Yuan Min, Shaw Chanh Op, Dwyer Dominic E, Saksena Nitin K
Abstract excerpt
BACKGROUND: HIV drug resistance mutations both in peripheral blood mononuclear cells (PBMCs) and plasma have the ability to influence the outcome of highly active antiretroviral therapy for HIV patients. PBMCs harbor archival proviral DNA, are a major source of HIV and also underdo latent infecti...
Topics
- Antiretroviral Therapy, Highly Active
- DNA, Viral
- Drug Resistance, Viral
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Microbial Sensitivity Tests
- Mutation
- Proviruses
- RNA, Viral
- Viral Load