Article
Risk assessment: the importance of genetic polymorphisms in man.
Mutation research - 1 Oct 2001
Knudsen L E, Loft S H, Autrup H
Abstract excerpt
Many genetic polymorphisms in metabolism enzymes are important for the risk of cancer as shown in a large number of case-control studies. The relative risk estimates have shown large variations between such population studies. However, in most studies the relative risk estimates are in the range of 2. Some polymorphisms are effect modifiers, i.e. without exposure they have no consequence and the effect of...
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