Article
Metabolic susceptibility genes as cancer risk factors: time for a reassessment?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2001
Garte S
Abstract excerpt
Polymorphisms in metabolic cancer susceptibility genes have not shown a consistent role as cancer risk factors, when only main effects are examined. This is actually to be expected given the limited and specific biochemical role such genes play in the carcinogenic process. However, when particular groups of case populations are examined separately, the importance of these genetic polymorphisms may often become...
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