Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism and their contribution to cancer susceptibility.

Cadernos de saude publica - 1 Jan 1998

Conforti-Froes N, el-Zein R, Au W

Abstract excerpt

Since the majority of chemical carcinogens are not capable of causing hazardous effects per se, the metabolism of these compounds is a crucial part of the initial host response to the environmental exposure. Disturbances in the balance between activation and detoxification may thus explain the individual variations in responses to exposures to carcinogens. The amount of the ultimate carcinogen produced depends on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 Enzyme System
Share to Environmental Exposure
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Glutathione Transferase

Share to Neoplasms

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 9819460
DOI: 10.1590/s0102-311x1998000700002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism and their contribution to cancer susceptibility.PMID 9819460Read ↗

Metabolic genotype in relation to individual susceptibility to environmental carcinogens.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.Semantic proximity Read ↗

The role of carcinogen-metabolizing enzyme polymorphisms in cancer susceptibility.Semantic proximity Read ↗

Genetic polymorphism of metabolic enzymes P450 (CYP) as a susceptibility factor for drug response, toxicity, and cancer risk.Semantic proximity Read ↗

Genetic polymorphism and cancer risk.Semantic proximity Read ↗

Ethnic and genetic differences in metabolism genes and risk of toxicity and cancer.Semantic proximity Read ↗

Assessment of cancer susceptibility in humans by use of genetic polymorphisms in carcinogen metabolism.Semantic proximity Read ↗

Modern cancer epidemiological research: genetic polymorphisms and environment.Semantic proximity Read ↗

Mechanisms of carcinogenesis and individual susceptibility to cancer.Semantic proximity Read ↗

Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response.Semantic proximity Read ↗

Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility.Semantic proximity Read ↗

Genetic susceptibility to environmental toxicants: the interface between human and experimental studies in the development of new toxicological concepts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.