Strategic issues in the design and interpretation of studies on metabolic polymorphisms and cancer.

Abstract excerpt

This chapter describes in a simple way the most important issues of epidemiological design, with emphasis on studies on metabolic polymorphisms. Different options are offered to the researcher who approaches a molecular epidemiology study. Case-control studies and cohort studies have different and sometimes complementary advantages and disadvantages. The sources of bias and the choice of controls, with specific...

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