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Article

Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo.

Development (Cambridge, England) - 1 Aug 2001

Stronach B E, Perrimon N

Abstract excerpt

The leading edge (LE) is a single row of cells in the Drosophila embryonic epidermis that marks the boundary between two fields of cells: the amnioserosa and the dorsal ectoderm. LE cells play a crucial role in the morphogenetic process of dorsal closure and eventually form the dorsal midline of the embryo. Mutations that block LE differentiation result in a failure of dorsal closure and embryonic lethality. How...

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Identifiers

PMID: 11532914
DOI: 10.1242/dev.128.15.2905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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