Article
Specialized extraembryonic cells connect embryonic and extraembryonic epidermis in response to Dpp during dorsal closure in Drosophila.
Developmental biology - 15 Jan 2007
Wada Atsushi, Kato Kagayaki, Uwo Makiko F, Yonemura Shigenobu, Hayashi Shigeo
Abstract excerpt
Dorsal closure in Drosophila embryogenesis involves expansion of the dorsal epidermis, followed by closure of the opposite epidermal edges. This process is driven by contractile force generated by an extraembryonic epithelium covering the yolk syncytium known as the amnioserosa. The secreted signaling molecule Dpp is expressed in the leading edge of the dorsal epidermis and is essential for dorsal closure. We...
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