Article
Planar polarity and actin dynamics in the epidermis of Drosophila.
Nature cell biology - 1 Dec 2002
Kaltschmidt Julia A, Lawrence Nicola, Morel Véronique, Balayo Tina, Fernández Beatriz García, Pelissier Anne, Jacinto Antonio, Martinez Arias Alfonso
Abstract excerpt
Dorsal closure is a morphogenetic process involving the coordinated convergence of two epithelial sheets to enclose the Drosophila melanogaster embryo. Specialized populations of cells at the edges of each epithelial sheet, the dorsal-most epidermal cells, emit actin-based processes that are essential for the proper enclosure of the embryo. Here we show that actin dynamics at the leading edge is preceded by a...
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