Article
Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing.
Science (New York, N.Y.) - 18 Mar 2005
Gibson Matthew C, Perrimon Norbert
Abstract excerpt
During animal development, epithelial cell fates are specified according to spatial position by extracellular signaling pathways. Among these, the transforming growth factor beta/bone morphogenetic protein (TGF-beta/BMP) pathways are evolutionarily conserved and play crucial roles in the development and homeostasis of a wide range of multicellular tissues. Here we show that in the developing Drosophila wing...
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