Article
Rapid mutational analysis of N-ras proto-oncogene in hematologic malignancies: study of 77 Greek patient.
Haematologica - 1 Sept 2001
Speletas M, Arvanitidi K, Tzoanopoulos D, Tsironidou V, Pardali E, Aggeli C, Tsapogas P, Kartalis G, Sideras P, Ritis K
Abstract excerpt
BACKGROUND AND OBJECTIVES: N-ras mutations are the most commonly detected molecular abnormalities in hematologic malignancies, especially in those of myeloid origin. Different techniques have been used to detect N-ras mutations; however, most of them are either labor intensive or provide sequence data for only a limited number of codons. Consequently, study of the N-ras oncogene has not been convenient in every...
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